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Custom Synthesis ADC-related Products
ADC drugs are highly cytotoxic chemical drugs coupled with monoclonal antibodies through linkers, integrating the high target specificity of antibody drugs and the high toxicity of small molecule toxins to achieve precise and efficient killing of tumor cells. Pharmalego offers custom synthesis services for ADC-related products such as toxin small molecules, Linkers and Payloads.
Production Capacity

Our scientific research team can meet client R&D needs from milligrams to kilograms for library toxins and linkers;

A full process service from drug R&D to preclinical CMC production, reducing R&D costs and improving the speed and efficiency of drug R&D.

Custom Process
01
Fill in the requirement form
02
Understand client needs and determine the contract plan
03
Arrange for synthesis
04
Purification and analysis
05
Packaging and delivery
Type
Type
Details
Payload
DX8951f, SN-38, DM1, DM4, Exatecan, Dxd, MMAE/MMAF, Tubulysin M, PBD dimer, Seco-Duocarmycin MA, PNU159682, Doxorubicin analog.
Linker
Various types of cleavable and uncleavable Linker;
Various types of hydrophilic and hydrophobic Linker;
New types of Linker, such as: Gly-Gly-Phe-Gly, VC-PAB, SMCC, N-SMP.
Payload+Linker
SN-38-PEG-PAB, DXD-GlyGlyPheGly, DXD-VCPABDM1-SMCC, DM1-SPP, DM4-SPDB, MC-VC-PAB-MMAE/MMAF, MC-Val-Ala-PBD, VC-PAB-Dolastatin 10.
small molecule toxins
DM1、MMAE、Exatecan、Dxd、SN38.
Targets
Her2, Her3, Trop2, Claudin 18.2, CD33, Muc1, FR.
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Custom Synthesis ADC-related Products

We will strictly follow the confidentiality agreement signed with the client to execute the services.

Custom services will be assessed to determine the corresponding plan and price.

For further information, please email marketing@pharmalego.com

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