Pharmalego - A Trusted Platform for Premium Pharmaceutical Intermediates

Pharmalego is a specialized company providing high-end pharmaceutical intermediates and custom synthesis services. With years of experience in the biopharmaceutical industry, advanced equipment, and innovative drug development technologies, we have established an integrated e-commerce platform encompassing the research, development, production, and sales of pharmaceutical intermediates. We offer a wide range of molecular building blocks and pharmaceutical intermediates and are committed to delivering top-quality custom synthesis solutions to our clients.

E3 Ligase-CRBN、E3 Ligase-VHL、PROTAC linker……
Common building blocks in literature are often hard to find in reality.
Are you also searching for these building blocks?

PROTAC Building Blocks

Pharmalego has developed over 600 linker and E3 ligase ligand building blocks, including common long carbon chains, ethylene glycol long chains, spiroheterocyclic chains, and ligands such as CRBN, VHL, cIAP, and MDM2.

E3 Ligase-CRBN: Over 100 types
E3 Ligase-VHL: Over 100 types
E3 Ligase-others : Over 50 types
PROTAC linkers: Over 1000 types

If we cannot meet your needs, we can also provide custom synthesis services.

Sugar unit intermediates, base intermediates, delivery systems...
These intermediates are not difficult to synthesize, but they require significant time and effort!br/> Are you also working endless overtime to tackle these challenges?

Nucleic Acid Drugs

Pharmalego provides efficient customization and R&D services for nucleic acid monomers and delivery systems. Currently, we offer over 300 synthetic building blocks to modify the ribose, base, phosphate backbone, and delivery systems, including GalNAc and LNP structures.

Key capabilities include:
Sugar modification: Over 100 sugar unit intermediates
Base modification: Over 50 base intermediates
Backbone modification: Extensive expertise in backbone modification chemistry
Delivery systems: 1500⁺ LNP and over 30 GalNAc synthesis projects

If we cannot meet your needs, we can also provide custom synthesis services.

ADC Linkers, Toxins, Payloads...
Missing even one intermediate can stall your research progress.
Are you also feeling stuck in such situations?

ADC

Pharmalego has R&D laboratories and highly active drug production capabilities. Our scientific team excels in chemical modification techniques, enabling us to provide in-house toxins and linkers for customer needs ranging from milligram to kilogram scales. We offer comprehensive services from drug discovery to preclinical CMC production.

Our expertise includes:
ADC Linkers: Over 300 types
Toxins: Over 50 types
Payloads: Over 30 types

Examples:
Calendula: MMAE, MMAF
Maytansinoids: DM1, DM4
Pyrrobenzazepines and chlorobenzazepines: PBD
Camptothecins: DX, SD38

If we cannot meet your needs, we can also provide custom synthesis services.

Benzene Ring Intermediates, Pyridine Intermediates, Deuterated Intermediates, Pyrimidine Intermediates...
Isn’t it time to streamline your research with high-quality intermediates?
Research and development can be challenging without the right tools and resources.
Are you often forced to start your projects from scratch?

Intermediates

Pharmalego offers a comprehensive range of pharmaceutical intermediates, including benzene ring intermediates, pyrimidine intermediates, pyridine intermediates, and various heterocyclic intermediates. We provide high-quality, high-purity intermediates to expedite target product development and meet diverse client needs.

Our expertise includes:
Benzene Ring Intermediates: Aniline, Phenol, Benzaldehyde, Phenyl ether, Phenylboronic acid, Benzoyl, Acetophenone, Biphenyl...
Pyridine Intermediates: Aminopyridine, Halopyridine, Pyridine boric acid, Hydroxypyridine, Cyanopyridine, Acylpyridine...
Deuterated Intermediates: Deuterated anisole
Pyrimidine Intermediates: Aminopyrimidine, Arylamine pyrimidine, Arylpyrimidine, Arylhydroxypyrimidine, Halopyrimidine, Hydroxypyrimidine...
Heterocyclic Intermediates: Benzopyrroles, Benzopyrans, Benzopyrazoles, Benzoxazines, Benzoxazoles...
Others: Amino acids, Naphthenes, Kinase inhibitors, Spiro rings, Bridge rings, Alkynes, Alkylamines, Alkyl acids, Alkenes...

If we cannot meet your needs, we can also provide custom synthesis services.

Does high-end always mean high price?
Is customization out of reach?
At Pharmalego, we believe in offering premium intermediates without compromising on quality, affordability, or safety.

Pharmalego Intermediate E-commerce Platform:
Easy to Use: Multiple compound search methods with traceable logistics information
Multiple Guarantees: QA/QC quality control with reliable after-sales service
People-Oriented: Comprehensive online consultation and feedback channels
Flexible Options: Online ordering, customization, and synthesis

Everything you need is here → https://cn.pharmalego.com